March 8, 1863 - Mary Cowan
The nickname history assigned her — "The Borgia of Maine" — reflects both the method and the intimacy of the harm: poison administered within her own household, to husbands and children alike, over the course of a decade. What makes Cowan's case historically notable is the sustained, domestic nature of the crimes, repeated across two marriages and into a third attempt before the pattern was recognized.
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